--- title: Biotech blog - Synthelis | Proteins description: Proteins | → Synthelis is a French biotech company specialized in production, purification and characterization of membrane proteins. Discover our biotech blog. --- [![](https://no-cache.hubspot.com/cta/default/4655509/57e4b5b9-17a7-4dea-b6e7-bd13a7d960ea.png)](https://cta-redirect.hubspot.com/cta/redirect/4655509/57e4b5b9-17a7-4dea-b6e7-bd13a7d960ea) [![Synthelis](https://blog.synthelis.com/hs-fs/hubfs/Synthelis_June2018_Theme/Images/logo.png?width=181&height=90&name=logo.png "Synthelis")](http://www.synthelis.com/) - [Twitter](https://twitter.com/Synthelis) - [Linkedin](https://www.linkedin.com/company/synthelis) - [RSS](http://www.synthelis.com/feed/) - [Contact](http://www.synthelis.com/contact/) - [Technology](http://www.synthelis.com/cell-free-technology/) - [Cell-Free for Membrane Proteins](http://www.synthelis.com/cell-free-technology/cell-free-for-membrane-proteins/) - [Cell-Free for soluble proteins](http://www.synthelis.com/cell-free-technology/cell-free-for-soluble-proteins/) - [Proteins inserted into a proteoliposome](http://www.synthelis.com/cell-free-technology/proteins-inserted-into-a-proteoliposomes/) - [Applications](http://www.synthelis.com/fields-of-application-for-membrane-proteins/) - [Vaccine development](http://www.synthelis.com/fields-of-application-for-membrane-proteins/vaccine-development/) - [Antibody development](http://www.synthelis.com/fields-of-application-for-membrane-proteins/antibody-development/) - [Screening & display technologies](http://www.synthelis.com/fields-of-application-for-membrane-proteins/screening-display-technologies/) - [Protein delivery](http://www.synthelis.com/fields-of-application-for-membrane-proteins/protein-delivery/) - [In vitro Diagnostics -IVD](http://www.synthelis.com/fields-of-application-for-membrane-proteins/in-vitro-diagnostics/) - [Structural Biology](http://www.synthelis.com/fields-of-application-for-membrane-proteins/structural-biology/) - [Solutions](http://www.synthelis.com/services-cell-free/) - [Products](http://www.synthelis.com/protein-catalogue/) - [Services](http://www.synthelis.com/services-cell-free/) - [Blog & News](https://blog.synthelis.com/) - [Blog](https://blog.synthelis.com/) - [News](https://www.synthelis.com/ressources/news/) - [Events](http://www.synthelis.com/synthelis-events/) - [Ressources](http://www.synthelis.com/publications/) - [About](http://www.synthelis.com/about/) - [Our Management](http://www.synthelis.com/about/synthelis-team/) - [Our History](http://www.synthelis.com/about/history/) - [Our Investors](http://www.synthelis.com/about/investors/) - [Our Clients](http://www.synthelis.com/about/clients/) - [Our Partners](http://www.synthelis.com/about/institutional-partners/) - [Our Distributors](http://www.synthelis.com/about/our-distributors/) - [They talked about us](http://www.synthelis.com/about/they-talked-about-us/) - [Contact](http://www.synthelis.com/contact/) - [Synthelis](http://www.synthelis.com/) - Synthelis - Biotech blog # Synthelis - Biotech blog [Need more information request a call back](https://blog.synthelis.com/request-a-call-back?hsLang=en-gb) [![Share on linkedin](https://blog.synthelis.com/hs-fs/hubfs/hs_marketplace_assets/modules/Social%20Sharing/79/linkedin-color.png?width=24&name=linkedin-color.png)](http://www.linkedin.com/shareArticle?mini=true&url=https://blog.synthelis.com/tag/proteins&utm_medium=social&utm_source=linkedin) [![Share on twitter](https://blog.synthelis.com/hs-fs/hubfs/hs_marketplace_assets/modules/Social%20Sharing/79/twitter-color.png?width=24&name=twitter-color.png)](https://twitter.com/intent/tweet?original_referer=https://blog.synthelis.com/tag/proteins&utm_medium=social&utm_source=twitter&url=https://blog.synthelis.com/tag/proteins&utm_medium=social&utm_source=twitter&source=tweetbutton&text=) ## [Mythbusting#1: Cell-free systems are only relevant for membrane proteins](https://blog.synthelis.com/mythbusting1cellfreesystems?hsLang=en-gb) Posted by [Bruno Tillier](https://blog.synthelis.com/author/bruno-tillier) on 2 Dec 2021, 14:20:47 [![Cell-free systems are only relevant for membrane proteins](https://blog.synthelis.com/hubfs/cell-free-systems-are-not-only-relevant-for-membrane%20proteins.png)](https://blog.synthelis.com/mythbusting1cellfreesystems?hsLang=en-gb) Cell-free protein synthesis (CFPS) methodology offers the possibility to produce proteins that would be difficult or even impossible to synthesize in cell-based systems. These so-called “difficult-to-express proteins” include membrane proteins, but also cytotoxic proteins (toxic cancer therapeutics, antimicrobial peptides/proteins and toxins), vaccines, antibodies and proteins containing non-standard amino acids \[1\]. Cell-free systems are, also, advantageous for the synthesis of proteins with biased coding sequences or with defined post-translational modifications, for the ones that require chaperones or specific chemical environments and even for the synthesis of virus-like particles and bacteriophages. [Read More](https://blog.synthelis.com/mythbusting1cellfreesystems?hsLang=en-gb) 0 Comments [Click here to read/write comments](https://blog.synthelis.com/mythbusting1cellfreesystems?hsLang=en-gb#comments-listing) Topics: [Cell-free technology](https://blog.synthelis.com/tag/cell-free-technology), [Proteins](https://blog.synthelis.com/tag/proteins) ## [Proteoliposomes - ideal model systems for membrane protein analysis](https://blog.synthelis.com/proteoliposomes-ideal-model-systems-for-membrane-protein-analysis?hsLang=en-gb) Posted by [Bruno Tillier](https://blog.synthelis.com/author/bruno-tillier) on 28 Jan 2021, 12:27:14 **Proteoliposomes – ideal model systems to study the structure and function of membrane proteins in semi-native environment by cryogenic electron microscopy** [Read More](https://blog.synthelis.com/proteoliposomes-ideal-model-systems-for-membrane-protein-analysis?hsLang=en-gb) 0 Comments [Click here to read/write comments](https://blog.synthelis.com/proteoliposomes-ideal-model-systems-for-membrane-protein-analysis?hsLang=en-gb#comments-listing) Topics: [Proteins](https://blog.synthelis.com/tag/proteins), [Proteoliposomes](https://blog.synthelis.com/tag/proteoliposomes) ## [Five reasons to label your proteins for NMR studies using cell-free systems.](https://blog.synthelis.com/five-reasons-to-label-your-proteins-for-nmr-studies-using-cell-free-systems?hsLang=en-gb) Posted by [Bruno Tillier](https://blog.synthelis.com/author/bruno-tillier) on 18 Sept 2019, 11:19:00 [![membrane\_proteins\_synthelis](https://blog.synthelis.com/hubfs/membrane_proteins_synthelis.jpg)](https://blog.synthelis.com/five-reasons-to-label-your-proteins-for-nmr-studies-using-cell-free-systems?hsLang=en-gb) *Isotope labelling has been used for over 40 years to facilitate the study of protein structure using nuclear magnetic resonance (NMR) spectroscopy. During that time, traditional expression systems such as in vivo protein synthesis were the preferred options for fabricating the labelled proteins. However, nearly a decade ago, it was discovered that cell-free protein expression offers **an abundance of beneficial properties** making it more adapted to the addition of isotopes than first thought. Here, we give you our top five reasons to use a cell-free system to label your proteins for your NMR study…* [Read More](https://blog.synthelis.com/five-reasons-to-label-your-proteins-for-nmr-studies-using-cell-free-systems?hsLang=en-gb) 0 Comments [Click here to read/write comments](https://blog.synthelis.com/five-reasons-to-label-your-proteins-for-nmr-studies-using-cell-free-systems?hsLang=en-gb#comments-listing) Topics: [Cell-free technology](https://blog.synthelis.com/tag/cell-free-technology), [Proteins](https://blog.synthelis.com/tag/proteins) [All posts](https://blog.synthelis.com/all) ### Topics - [Cell-free technology (3)](https://blog.synthelis.com/tag/cell-free-technology) - [Proteins (3)](https://blog.synthelis.com/tag/proteins) - [Proteoliposomes (1)](https://blog.synthelis.com/tag/proteoliposomes) ### Latest articles ### Subscribe to our blog [![Synthelis](https://blog.synthelis.com/hubfs/Synthelis_June2018_Theme/Images/logo-footer.png)](http://www.synthelis.com/) - [Facebook](https://www.facebook.com/synthelis) - [Twitter](https://twitter.com/Synthelis) - [Linkedin](https://www.linkedin.com/company/synthelis) - [RSS](http://www.synthelis.com/feed/) - [Contact](https://blog.synthelis.com/request-a-call-back?hsLang=en-gb) - [Cell-Free Technology](http://www.synthelis.com/cell-free-technology/) - [Applications](http://www.synthelis.com/fields-of-application-for-membrane-proteins/) - [Services](http://www.synthelis.com/services-cell-free/) - [Products](http://www.synthelis.com/products/) - [Synthelis](http://www.synthelis.com/about/) - [News & Events](http://www.synthelis.com/ressources/news/) - [Resources](http://www.synthelis.com/publications/) - [Privacy policy](http://www.synthelis.com/privacy-policy/)